SH2B2 抗体 (N-Term)
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北京 101111
Quick Overview for SH2B2 抗体 (N-Term) (ABIN6256908)
抗原
See all SH2B2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- SH2B2 Antibody detects endogenous levels of total SH2B2.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SH2B2, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-SH2B Adaptor Protein 2 (SH2B2) antibody
SH2B2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SH2B Adaptor Protein 2 (SH2B2) (Internal Region) antibodySH2B2 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SH2B2 (SH2B Adaptor Protein 2 (SH2B2))
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别名
- SH2B2
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背景
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Description: Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways. May be involved in coupling from immunoreceptor to Ras signaling. Acts as a negative regulator of cytokine signaling in collaboration with CBL. Binds to EPOR and suppresses EPO-induced STAT5 activation, possibly through a masking effect on STAT5 docking sites in EPOR. Suppresses PDGF-induced mitogenesis. May induce cytoskeletal reorganization via interaction with VAV3.
Gene: SH2B2
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分子量
- 67 kDa
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基因ID
- 10603
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UniProt
- O14492
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途径
- Carbohydrate Homeostasis, Brown Fat Cell Differentiation
抗原
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