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IQGAP1 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects IQGAP1 in WB, ELISA, IF 和 ICC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN6256871
发货至: 中国
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Quick Overview for IQGAP1 抗体 (N-Term) (ABIN6256871)

抗原

See all IQGAP1 抗体
IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

适用

  • 71
  • 35
  • 19
  • 15
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 67
  • 5
  • 1

克隆类型

  • 48
  • 25
多克隆

标记

  • 31
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IQGAP1 antibody is un-conjugated

应用范围

  • 57
  • 22
  • 22
  • 18
  • 14
  • 14
  • 14
  • 13
  • 7
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    IQGAP1 Antibody detects endogenous levels of total IQGAP1.

    预测反应

    Pig,Bovine,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human IQGAP1, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    IQGAP1 (IQ Motif Containing GTPase Activating Protein 1 (IQGAP1))

    别名

    IQGAP1

    背景

    Description: Plays a crucial role in regulating the dynamics and assembly of the actin cytoskeleton. Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth (PubMed:15695813). May play a possible role in cell cycle regulation by contributing to cell cycle progression after DNA replication arrest (PubMed:20883816).

    Gene: IQGAP1

    分子量

    190 kDa

    基因ID

    8826

    UniProt

    P46940

    途径

    Signaling Events mediated by VEGFR1 and VEGFR2
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