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PIK3R1 抗体 (pTyr607)

Name: PIK3R1 抗体 (pTyr607)
SKU: ABIN6256775
Availability: OutOfStock

This anti-PIK3R1 antibody is a 兔多克隆 antibody detecting PIK3R1 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠, 大鼠和 Pig. This Primary Antibody has been cited in 5+ publications.

Western blot analysis of Phospho-PI3K p85 alpha (Tyr607) expression in Mouse heart tissue lysate (PIK3R1 抗体 (pTyr607))

ABIN6267452 at 1/100 staining rat kidney tissue sections by IHC-P. (PIK3R1 抗体 (pTyr607))

IHC

ABIN6267452 at 1/200 staining human colon cancer tissue sections by IHC-P. (PIK3R1 抗体 (pTyr607))

IHC

ABIN6267452 at 1/200 staining human bladder cancer tissue sections by IHC-P. (PIK3R1 抗体 (pTyr607))

29 images

(5 references)

产品编号 ABIN6256775

发货至: 中国

Datasheet as PDF

Quick Overview for PIK3R1 抗体 (pTyr607) (ABIN6256775)

抗原

See all PIK3R1 (PI3K p85a) 抗体

PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

适用

人, 小鼠, 大鼠, Pig

宿主

兔

克隆类型

多克隆

标记

This PIK3R1 antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Discover our top product PI3K p85a Primary Antibody

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pTyr607

特异性

Phospho-PI3-kinase p85- alpha (Tyr607) Antibody detects endogenous levels of PI3-kinase p85- alpha only when phosphorylated at Tyrosine 607

交叉反应

人, 小鼠, 猪, 大鼠

纯化方法

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

免疫原

A synthesized peptide derived from human PI3-kinase p85- alpha around the phosphorylation site of Tyrosine 607

亚型

IgG
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 1-454) antibody
PI3K p85a 适用: 人 WB, ELISA, IP, PLA 宿主: 小鼠 Monoclonal 3A10 unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 159-388) antibody
PI3K p85a 适用: 人, 小鼠 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 6G10 unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 501-600) antibody
PI3K p85a 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 1-30), (N-Term) antibody
PI3K p85a 适用: 人, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB11634 unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 159-388) antibody
PI3K p85a 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 15-180) antibody
PI3K p85a 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) antibody
PI3K p85a 适用: 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 3B7 unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 1-424) antibody
PI3K p85a 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (C-Term) antibody
PI3K p85a 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (pTyr368) antibody
PI3K p85a 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C.Stable for 12 months from date of receipt

有效期

12 months
Chang, Guo, Zhou, Huang, Yi, Dou, Huan: "HBP induces the expression of monocyte chemoattractant protein-1 via the FAK/PI3K/AKT and p38 MAPK/NF-κB pathways in vascular endothelial cells." in: Cellular signalling, Vol. 43, pp. 85-94, (2018) (PubMed).

Chai, Bai, Li, Chen, Zhang: "Biological functions of lung cancer cells are suppressed in co-culture with mesenchymal stem cells isolated from umbilical cord." in: Experimental and therapeutic medicine, Vol. 15, Issue 1, pp. 1076-1080, (2018) (PubMed).

Liu, Geng, Zhang, Wang, Zhang, Duan, Zhang: "Oligo-Porphyran Ameliorates Neurobehavioral Deficits in Parkinsonian Mice by Regulating the PI3K/Akt/Bcl-2 Pathway." in: Marine drugs, Vol. 16, Issue 3, (2018) (PubMed).

Wang, Li, Chen, Yang: "Umbilical cord‑derived mesenchymal stem cells can inhibit the biological functions of melanoma A375 cells." in: Oncology reports, Vol. 40, Issue 1, pp. 511-517, (2018) (PubMed).

Shang, Wang, Tong, Kang, Liang, Ge: "Prolyl hydroxylases positively regulated LPS-induced inflammation in human gingival fibroblasts via TLR4/MyD88-mediated AKT/NF-κB and MAPK pathways." in: Cell proliferation, pp. e12516, (2018) (PubMed).
抗原

PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

别名

PI3K p85 alpha

背景

Description: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling (PubMed:17626883, PubMed:19805105, PubMed:7518429). Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (PubMed:20348923).
Gene: PIK3R1

分子量

80kDa

基因ID

5295

UniProt

P27986

途径

TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effect