NCOA3 抗体 (pThr24)
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北京 101111
Quick Overview for NCOA3 抗体 (pThr24) (ABIN6256520)
抗原
See all NCOA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr24
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特异性
- Phospho-SRC-3 (Thr24) Antibody detects endogenous levels of SRC-3.
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交叉反应
- 人, 小鼠
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human SRC-3 around the phosphorylation site of Thr24.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))
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别名
- SRC-3
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背景
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Description: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.
Gene: NCOA3
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分子量
- 160kDa
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基因ID
- 8202
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UniProt
- Q9Y6Q9
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha
抗原
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