Synaptotagmin 抗体 (pThr202)
Quick Overview for Synaptotagmin 抗体 (pThr202) (ABIN6256502)
抗原
See all Synaptotagmin (SYT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr202
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特异性
- Phospho-Synaptotagmin (Thr202) Antibody detects endogenous levels of Synaptotagmin only when phosphorylated at Threonine 202
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human Synaptotagmin around the phosphorylation site of Threonine 202
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亚型
- IgG
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- Synaptotagmin (SYT)
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别名
- Synaptotagmin
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背景
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Description: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner, these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Gene: SYT1
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分子量
- 60kDa
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基因ID
- 6857
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UniProt
- P21579, Q8N9I0
抗原
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