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PDCD4 抗体 (pSer67)

This anti-PDCD4 antibody is a 兔 多克隆 antibody detecting PDCD4 in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6256398
发货至: 中国

Quick Overview for PDCD4 抗体 (pSer67) (ABIN6256398)

抗原

See all PDCD4 抗体
PDCD4 (Programmed Cell Death 4 (PDCD4))

适用

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  • 62
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  • 3
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人, 小鼠, 大鼠

宿主

  • 92
  • 7
  • 2
  • 1

克隆类型

  • 87
  • 15
多克隆

标记

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  • 4
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This PDCD4 antibody is un-conjugated

应用范围

  • 78
  • 45
  • 35
  • 13
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  • 6
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  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 9
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    • 6
    • 5
    • 3
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    • 2
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer67

    特异性

    Phospho-PDCD4 (Ser67) Antibody detects endogenous levels of PDCD4 only when phosphorylated at Serine 67.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human PDCD4 around the phosphorylation site of Ser67.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    PDCD4 (Programmed Cell Death 4 (PDCD4))

    别名

    PDCD4

    背景

    Description: Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).

    Gene: PDCD4

    分子量

    56kDa

    基因ID

    27250

    UniProt

    Q53EL6
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