RanBP3 抗体 (pSer58, pSer126)
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Quick Overview for RanBP3 抗体 (pSer58, pSer126) (ABIN6256379)
抗原
See all RanBP3 (RANBP3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer58, pSer126
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特异性
- Phospho-RanBP3 (Ser126/58) Antibody detects endogenous levels of RanBP3.
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交叉反应
- 人, 小鼠
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human RanBP3 around the phosphorylation site of Ser126/58.
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亚型
- IgG
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anti-RAN Binding Protein 3 (RANBP3) (AA 298-397) antibody
RANBP3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-RAN Binding Protein 3 (RANBP3) (AA 150-200) antibodyRANBP3 适用: 人, 小鼠 IHC, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 3 (RANBP3) (AA 1-250) antibodyRANBP3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 3 (RANBP3) antibodyRANBP3 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB1315 unconjugated Recombinant Antibody
anti-RAN Binding Protein 3 (RANBP3) (AA 1-250) antibodyRANBP3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- RanBP3 (RANBP3) (RAN Binding Protein 3 (RANBP3))
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别名
- RanBP3
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背景
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Description: Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.
Gene: RANBP3
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分子量
- 70kDa
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基因ID
- 8498
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UniProt
- Q9H6Z4
抗原
-
