HNRNPC 抗体 (pSer260)
Quick Overview for HNRNPC 抗体 (pSer260) (ABIN6256225)
抗原
See all HNRNPC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer260
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特异性
- Phospho-hnRNP C1/C2 (Ser260) Antibody detects endogenous levels of hnRNP C1/C2 only when phosphorylated at Serine 260.
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预测反应
- Horse,Rabbit,Dog,Xenopus
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human hnRNP C1/C2 around the phosphorylation site of Ser260.
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亚型
- IgG
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anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibody
KO Validated HNRNPC 适用: 人 WB, IF, IHC (p), ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibodyHNRNPC 适用: 人 WB, IHC, ELISA, IF, IP, FACS 宿主: 兔 Monoclonal 9G1 unconjugated Recombinant Antibody
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 1-250) antibodyHNRNPC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E8 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) antibodyHNRNPC 适用: 人, 兔, Cow, 犬, Pig, 猴, 马, 山羊, 豚鼠, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 241-290) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (AA 1-142), (N-Term) antibodyHNRNPC 适用: 人, 大鼠, 小鼠, 兔, Cow WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) antibodyHNRNPC 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (C-Term) antibodyHNRNPC 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC) (pSer260) antibodyHNRNPC 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
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别名
- HNRNPC
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背景
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Description: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621). Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides (PubMed:8264621). May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm6A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671).
Gene: HNRNPC
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分子量
- 41kDa
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基因ID
- 3183
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UniProt
- P07910
抗原
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