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Filamin A 抗体 (pSer2152)

This anti-Filamin A antibody is a 兔 多克隆 antibody detecting Filamin A in WB, IHC, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6256196
发货至: 中国

Quick Overview for Filamin A 抗体 (pSer2152) (ABIN6256196)

抗原

See all Filamin A (FLNA) 抗体
Filamin A (FLNA) (Filamin A, alpha (FLNA))

适用

  • 108
  • 33
  • 22
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  • 1
人, 小鼠, 大鼠

宿主

  • 99
  • 9
  • 1

克隆类型

  • 87
  • 22
多克隆

标记

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  • 2
  • 2
  • 2
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This Filamin A antibody is un-conjugated

应用范围

  • 57
  • 34
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  • 28
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  • 24
  • 15
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  • 9
  • 7
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
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    pSer2152

    特异性

    Phospho-Filamin A (Ser2152) Antibody detects endogenous levels of Filamin A only when phosphorylated at Serine 2152.

    预测反应

    Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human Filamin A around the phosphorylation site of Ser2152.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:100-1:500, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    Filamin A (FLNA) (Filamin A, alpha (FLNA))

    别名

    FLNA

    背景

    Description: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity).

    Gene: FLNA

    分子量

    280kDa

    基因ID

    2316

    UniProt

    P21333

    途径

    TCR Signaling, Maintenance of Protein Location
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