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SMAD1 抗体 (pSer187)

This anti-SMAD1 antibody is a 兔 多克隆 antibody detecting SMAD1 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6256175
发货至: 中国

Quick Overview for SMAD1 抗体 (pSer187) (ABIN6256175)

抗原

See all SMAD1 抗体
SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

适用

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宿主

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克隆类型

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多克隆

标记

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This SMAD1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
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    pSer187

    特异性

    Phospho-Smad1 (Ser187) Antibody detects endogenous levels of Smad1 only when phosphorylated at Serine 187.

    预测反应

    Bovine,Sheep,Rabbit,Chicken,Xenopus

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human Smad1 around the phosphorylation site of Ser187.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • Yi, Yu, Yang, Miron, Zhang: "Tcf12, A Member of Basic Helix-Loop-Helix Transcription Factors, Mediates Bone Marrow Mesenchymal Stem Cell Osteogenic Differentiation In Vitro and In Vivo." in: Stem cells (Dayton, Ohio), Vol. 35, Issue 2, pp. 386-397, (2017) (PubMed).

  • 抗原

    SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))

    别名

    SMAD1

    背景

    Description: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

    Gene: SMAD1

    分子量

    60/55kDa

    基因ID

    4086

    UniProt

    Q15797

    途径

    Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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