EIF3B 抗体 (pSer154)
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北京 101111
Quick Overview for EIF3B 抗体 (pSer154) (ABIN6256153)
抗原
See all EIF3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer154
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特异性
- Phospho-EIF3B(Ser154) Antibody detects endogenous levels of EIF3B.
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human EIF3B around the phosphorylation site of Ser154.
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亚型
- IgG
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anti-Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B) antibody
KD Validated EIF3B 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4545 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B) (AA 100-150) antibodyEIF3B 适用: 人, 小鼠 IHC, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B) (AA 100-350) antibodyEIF3B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B) antibodyEIF3B 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B) antibodyEIF3B 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3830 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B) antibodyEIF3B 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4540 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B) (AA 100-150) antibodyEIF3B 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B) (C-Term) antibodyEIF3B 适用: 人, 小鼠, 大鼠, 马, 犬, 豚鼠, 兔, 斑马鱼, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B) (C-Term) antibodyEIF3B 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B) (AA 100-150) antibodyEIF3B 适用: 人, 小鼠 IF, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- EIF3B (Eukaryotic Translation Initiation Factor 3, Subunit B (EIF3B))
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别名
- EIF3B
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背景
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Description: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:9388245, PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Gene: EIF3B
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分子量
- 116 kDa
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基因ID
- 8662
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UniProt
- P55884
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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