CD79a 抗体 (pTyr182)
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北京 101111
Quick Overview for CD79a 抗体 (pTyr182) (ABIN6255832)
抗原
See all CD79a (CD79A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr182
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特异性
- Phospho-CD79A (Tyr182) Antibody detects endogenous levels of CD79A.
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交叉反应
- 人, 小鼠
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human CD79A around the phosphorylation site of Tyr182.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))
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别名
- CD79A
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背景
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Description: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.
Gene: CD79A
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分子量
- 45-55kDa
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基因ID
- 973
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UniProt
- P11912
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途径
- BCR Signaling
抗原
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