Caveolin-1 抗体 (pTyr14)
Quick Overview for Caveolin-1 抗体 (pTyr14) (ABIN6255810)
抗原
See all Caveolin-1 (CAV1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr14
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特异性
- Phospho-Caveolin 1 (Tyr14) Antibody detects endogenous levels of Caveolin 1 only when phosphorylated at Tyrosine 14.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human Caveolin 1 around the phosphorylation site of Tyr14.
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亚型
- IgG
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anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (N-Term) antibody
KO Validated CAV1 适用: 人 WB, IF, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-104) antibodyCAV1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-104) antibodyCAV1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-105) antibodyCAV1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (Internal Region) antibodyVerified CAV1 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 1-100) antibodyCAV1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 2-120) antibodyCAV1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 4-178) antibodyCAV1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (AA 4-178) antibodyCAV1 适用: 人, 小鼠 WB, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (N-Term) antibodyCAV1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
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别名
- CAV1
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背景
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Description: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway. Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (PubMed:25893292). Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (PubMed:19262564).
Gene: CAV1
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分子量
- 23kDa
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基因ID
- 857
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UniProt
- Q03135
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途径
- Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
抗原
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