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Caldesmon 抗体 (pSer789)

This anti-Caldesmon antibody is a 兔 多克隆 antibody detecting Caldesmon in WB, IHC, ELISA, IF 和 ICC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6255507
发货至: 中国

Quick Overview for Caldesmon 抗体 (pSer789) (ABIN6255507)

抗原

See all Caldesmon (CALD1) 抗体
Caldesmon (CALD1) (Caldesmon 1 (CALD1))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Caldesmon antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    pSer789

    特异性

    Phospho-Caldesmon (Ser789) Antibody detects endogenous levels of Caldesmon only when phosphorylated at Serine 789.

    预测反应

    Pig,Horse,Sheep,Rabbit,Dog

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human Caldesmon around the phosphorylation site of Ser789.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    Caldesmon (CALD1) (Caldesmon 1 (CALD1))

    别名

    CALD1

    背景

    Description: Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration (By similarity).

    Gene: CALD1

    分子量

    80kDa

    基因ID

    800

    UniProt

    Q05682

    途径

    Myometrial Relaxation and Contraction
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