EIF2S1 抗体 (pSer51)
(2 references)Quick Overview for EIF2S1 抗体 (pSer51) (ABIN6255389)
抗原
See all EIF2S1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer51
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特异性
- Phospho-eIF2 alpha (Ser51) Antibody detects endogenous levels of eIF2 alpha only when phosphorylated at Ser52, which site historically referenced as Ser51.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human eIF2 alpha around the phosphorylation site of Ser51.
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亚型
- IgG
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anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 1-315) antibody
EIF2S1 适用: 人 WB, IF, ELISA, RNAi 宿主: 小鼠 Monoclonal 3H12-C11 unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibodyEIF2S1 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 5A5 unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (N-Term) antibodyEIF2S1 适用: 人, 小鼠, 大鼠, Pig WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer51) antibodyEIF2S1 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Monoclonal 1C6 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer51) antibodyEIF2S1 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (pSer49) antibodyEIF2S1 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibodyEIF2S1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) antibodyEIF2S1 适用: 人, 大鼠, 犬, 猴 WB, FACS 宿主: 小鼠 Monoclonal 3H7 unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (AA 276-315) antibodyEIF2S1 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (C-Term) antibodyEIF2S1 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, Pig, 猴, 兔, 豚鼠, 小鸡, 马, 山羊, Bat, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:500, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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: "Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78." in: Cell death & disease, Vol. 9, Issue 6, pp. 636, (2018) (PubMed).
: "EndophilinA2 protects against angiotensin II-induced cardiac hypertrophy by inhibiting angiotensin II type 1 receptor trafficking in neonatal rat cardiomyocytes." in: Journal of cellular biochemistry, (2018) (PubMed).
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: "Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78." in: Cell death & disease, Vol. 9, Issue 6, pp. 636, (2018) (PubMed).
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- EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
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别名
- EIF2S1
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背景
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Description: Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
Gene: EIF2S1
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分子量
- 38kDa
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基因ID
- 1965
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UniProt
- P05198
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途径
- Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C
抗原
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