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tau 抗体 (pSer416)

The 兔 多克隆 anti-tau antibody (ABIN6255313) specifically detects tau in WB 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6255313
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for tau 抗体 (pSer416) (ABIN6255313)

抗原

See all tau 抗体
tau (tau Protein)

适用

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人, 小鼠, 大鼠

宿主

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  • 41
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克隆类型

  • 630
  • 167
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多克隆

标记

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This tau antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    pSer416

    特异性

    Phospho-Tau (Ser416) Antibody detects endogenous levels of Tau.

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human Tau around the phosphorylation site of Ser416.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C.Stable for 12 months from date of receipt

    有效期

    12 months
  • 抗原

    tau (tau Protein)

    别名

    Tau

    背景

    Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

    Gene: MAPT

    分子量

    50-80kDa

    基因ID

    4137

    UniProt

    P10636
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