RACGAP1 抗体 (pSer387)
Quick Overview for RACGAP1 抗体 (pSer387) (ABIN6255287)
抗原
See all RACGAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer387
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特异性
- Phospho-GTPase Activating Protein (Ser387) Antibody detects endogenous levels of GTPase Activating Protein only when phosphorylated at Serine 387
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交叉反应
- 人, 猴, 小鼠, 大鼠
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human GTPase Activating Protein around the phosphorylation site of Serine 387
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亚型
- IgG
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anti-Rac GTPase Activating Protein 1 (RACGAP1) (C-Term) antibody
Verified RACGAP1 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Rac GTPase Activating Protein 1 (RACGAP1) (AA 1-110) antibodyRACGAP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G6 unconjugated
anti-Rac GTPase Activating Protein 1 (RACGAP1) (N-Term) antibodyRACGAP1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Rac GTPase Activating Protein 1 (RACGAP1) (AA 353-632) antibodyRACGAP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Rac GTPase Activating Protein 1 (RACGAP1) (AA 353-632) antibodyRACGAP1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Rac GTPase Activating Protein 1 (RACGAP1) (AA 23-50), (N-Term) antibodyRACGAP1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB19807 unconjugated
anti-Rac GTPase Activating Protein 1 (RACGAP1) (AA 30-58), (N-Term) antibodyRACGAP1 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Rac GTPase Activating Protein 1 (RACGAP1) (pSer387) antibodyRACGAP1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Rac GTPase Activating Protein 1 (RACGAP1) (AA 86-331) antibodyRACGAP1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Rac GTPase Activating Protein 1 (RACGAP1) antibodyRACGAP1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))
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别名
- GTPase Activating Protein
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背景
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Description: Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.
Gene: RACGAP1
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分子量
- 72kDa
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基因ID
- 29127
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UniProt
- Q9H0H5
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途径
- Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
抗原
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