Histone H4 抗体 (meLys20)
Quick Overview for Histone H4 抗体 (meLys20) (ABIN6254918)
抗原
See all Histone H4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- meLys20
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特异性
- Histone H4K20me1 Antibody detects endogenous levels of total Histone H4K20me1
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交叉反应
- 人, 小鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthetic peptide corresponding to the amino terminus of histone H4 in which Lys20 is mono-methylated.
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亚型
- IgG
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应用备注
- WB 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- Histone H4
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别名
- Histone H4K20me1
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背景
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Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene: HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4
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分子量
- 11kDa
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基因ID
- 121, 504, 554
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UniProt
- P62805
抗原
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