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VCAM1 抗体 (FITC)

VCAM1 适用: 人 FACS, ICC 宿主: 小鼠 Monoclonal B-K9 FITC
产品编号 ABIN6253936
发货至: 中国
  • 抗原 See all VCAM1 抗体
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This VCAM1 antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS), Immunocytochemistry (ICC)
    特异性
    B-K9 produces mouse IgG1 immunoglobulins directed against a 110 kD protein known as human CD106. It reacts with approximately 15% of peripheral lymphocytes and between 30-90% activated HUVEC
    克隆位点
    B-K9
    亚型
    IgG1
    Top Product
    Discover our top product VCAM1 Primary Antibody
  • 应用备注
    tochemistry on cytospots,  immunohistochemistry on frozen tissue sections
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    4 °C
  • 抗原
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    别名
    CD106 (VCAM1 产品)
    别名
    CD106 antibody, INCAM-100 antibody, Vcam-1 antibody, VCAM1B antibody, fi76d06 antibody, wu:fi76d06 antibody, zgc:158875 antibody, VCAM1 antibody, vascular cell adhesion molecule 1 antibody, vascular cell adhesion molecule 1b antibody, VCAM1 antibody, Vcam1 antibody, vcam1b antibody, VCAM-1 antibody
    背景
    Antigen distribution: CD106 antigen binds the integrins a4b1 (CD49d/CD29, VLA-4) and a4b7 [4]. VLA-4 is the dominant ligand in cells expressing both integrins. Endothelial CD106 contributes to the extravasation of lymphocytes, monocytes, basophils and eosinophils (but not neutrophils) from blood vessels, especially at sites of inflammation. The VLA-4 interaction can mediate both the initial tethering and rolling of lymphocytes on endothelium as well as their subsequent arrest and firm adhesion [5]. CD106 expression on non-vascular tissues is thought to play a role in the interaction of hematopoietic progenitors with bone marrow stromal cells, B cell binding to follicular dendritic cells, co-stimulation of T cells and embryonic development [1,2,3]. Cellular Expression: VCAM-1. Vascular endothelium, dendritic cells, macrophages
    途径
    Carbohydrate Homeostasis
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