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CD16 抗体

CD16 适用: 人 FACS, ICC 宿主: 小鼠 Monoclonal B-E16 unconjugated
产品编号 ABIN6253847
发货至: 中国
  • 抗原 See all CD16 抗体
    CD16
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD16 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunocytochemistry (ICC)
    特异性
    B-E16 produces mouse IgG2a immunoglobulins specific for a 50-70 kD antigen which is associated with the IgG FceRI on NK cells, neutrophils, granulocytes and monocytes [3]
    纯度
    PURE
    克隆位点
    B-E16
    亚型
    IgG2a
    Top Product
    Discover our top product CD16 Primary Antibody
  • 应用备注
    immunohistochemistry on cytospots,  immunohistochemistry on frozen tissue
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    4 °C
  • 抗原
    CD16
    别名
    CD16 (CD16 产品)
    别名
    Fcgr3 antibody, Fcgr3a antibody, CD16 antibody, FCGR3 antibody, FCGR3@ antibody, CD16b antibody, FCG3 antibody, FCR-10 antibody, FCRIII antibody, FCRIIIb antibody, FcRIII antibody, Fc fragment of IgG, low affinity IIa, receptor antibody, Fc fragment of IgG, low affinity IIIa, receptor (CD16a) antibody, Fc fragment of IgG receptor IIIb antibody, Fc fragment of IgG receptor IIIa antibody, Fc receptor, IgG, low affinity III antibody, Fc-gamma RIII antibody, Fcgr2a antibody, FCGR3A antibody, FCGR3B antibody, Fcgr3 antibody, FCGR3 antibody
    背景
    Antigen distribution: CD16 is a low-affinity receptor for aggregated IgG (FcgRIII) [1,2]. The transmembrane form of CD16 is expressed on approximately 15% of peripheral blood lymphocytes and is present on virtually all resting NK cells. It is also found on macrophages and mast cells. It binds IgG complexed to antigens and mediates phagocytosis and antibody-dependent cellular cytotoxicity. On NK cells it mediates signal transduction while the GPI-linked form on neutrophils binds to ligands but is unable to induce any signal or functional effect [1]. Cellular Expression: NK cells, neutrophils, granulocytes, macrophages.
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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