CD16 抗体
Quick Overview for CD16 抗体 (ABIN6253847)
抗原
See all CD16 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- B-E16 produces mouse IgG2a immunoglobulins specific for a 50-70 kD antigen which is associated with the IgG FceRI on NK cells, neutrophils, granulocytes and monocytes [3]
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纯度
- PURE
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亚型
- IgG2a
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应用备注
- immunohistochemistry on cytospots, immunohistochemistry on frozen tissue
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C
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- CD16
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别名
- CD16
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背景
- Antigen distribution: CD16 is a low-affinity receptor for aggregated IgG (FcgRIII) [1,2]. The transmembrane form of CD16 is expressed on approximately 15% of peripheral blood lymphocytes and is present on virtually all resting NK cells. It is also found on macrophages and mast cells. It binds IgG complexed to antigens and mediates phagocytosis and antibody-dependent cellular cytotoxicity. On NK cells it mediates signal transduction while the GPI-linked form on neutrophils binds to ligands but is unable to induce any signal or functional effect [1]. Cellular Expression: NK cells, neutrophils, granulocytes, macrophages.
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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