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CD16 抗体

This anti-CD16 antibody is a 小鼠 单克隆 antibody detecting CD16 in FACS 和 ICC. Suitable for 人.
产品编号 ABIN6253847
发货至: 中国

Quick Overview for CD16 抗体 (ABIN6253847)

抗原

See all CD16 抗体
CD16

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD16 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

B-E16
  • 特异性

    B-E16 produces mouse IgG2a immunoglobulins specific for a 50-70 kD antigen which is associated with the IgG FceRI on NK cells, neutrophils, granulocytes and monocytes [3]

    纯度

    PURE

    亚型

    IgG2a
  • 应用备注

    immunohistochemistry on cytospots,  immunohistochemistry on frozen tissue

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    4 °C
  • 抗原

    CD16

    别名

    CD16

    背景

    Antigen distribution: CD16 is a low-affinity receptor for aggregated IgG (FcgRIII) [1,2]. The transmembrane form of CD16 is expressed on approximately 15% of peripheral blood lymphocytes and is present on virtually all resting NK cells. It is also found on macrophages and mast cells. It binds IgG complexed to antigens and mediates phagocytosis and antibody-dependent cellular cytotoxicity. On NK cells it mediates signal transduction while the GPI-linked form on neutrophils binds to ligands but is unable to induce any signal or functional effect [1]. Cellular Expression: NK cells, neutrophils, granulocytes, macrophages.

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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