DF1524 produces IgG2b mouse immunoglobulins specific for CD11a. It can be used for flow cytometry and immunohistochemistry for the detection of CD11a positive leucocytes
immunohistochemistry on cytospots, Immunohistochemistry on frozen tissue sections
限制
仅限研究用
状态
Liquid
储存条件
4 °C
抗原
ITGAL
(Integrin alpha-L (ITGAL))
别名
CD11a
背景
Antigen distribution: CD11a antigens are expressed on lymphocytes, granulocytes, monocytes and macrophages, with increased levels on memory T cells [1,2]. CD11a (integrinaL subunit) combines with CD18 (integrin b2 subunit) to form the integrin LFA-1 (CD11a/CD18). The three ligands for LFA-1 are CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3), each of which contains IgSF domains. DF1524 was clustered at the Leucocyte Typing Workshop IV [5]. Cellular Expression: Lymphocytes, granulocytes, monocytes and macrophages.