Recombinant DLG4 抗体
Quick Overview for Recombinant DLG4 抗体 (ABIN6253485)
抗原
See all DLG4 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-PSD-95 (palmitoylated), mAb (rec.) (PF11)
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产品特性
- Recombinant Antibody. Recognizes human, mouse and rat palmitoylated PSD-95. Isotype: Human IgG2. Clone: PF11. Applications: ICC, IHC. Liquid. In PBS containing 10 % glycerol. PSD-95 is a member of proteins located at a specialized postsynaptic membrane region, called the postsynaptic density (PSD). PSD-95 is the most abundant scaffold protein specifically enriched in the PSD. It contains three PDZ domains, an SH3 domain and a guanylate kinase (GuK)-like domain. Through its PDZ domains, PSD-95 assembles various synaptic components at the PSD including intracellular signaling molecules (e.g. SynGAP and kalirin-7), ion channels (e.g. stargazin/AMPA receptors [AMPARs] and NMDA receptors) and cell adhesion molecules (e.g. neuroligin). PSD-95 plays a primary role in synaptic development and maturation and is regulated by palmitoylation at its N-terminal cysteine residues leading to its postsynaptic targeting. Palmitoylation of PSD-95 is triggered by DHHC2, a plasma membrane-inserted palmitoylating enzyme. Palmitoylated PSD-95 is almost exclusively localized at excitatory synapses in neurons.
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纯度
- >95 % (SDS-PAGE)
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免疫原
- Palmitoylated PSD-95.
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亚型
- IgG2
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anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody
DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA, mIHC 宿主: 小鼠 Monoclonal 6G6 unconjugated
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) (C-Term) antibodyDLG4 适用: 大鼠, 人, 小鼠 WB, IHC, ELISA, IF, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibodyDLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 unconjugated
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (HRP)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 HRP
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (FITC)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 FITC
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Biotin)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 Biotin
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (PE)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 PE
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (PerCP)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 PerCP
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (APC)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 APC
anti-Discs, Large Homolog 4 (Drosophila) (DLG4) antibody (Atto 488)DLG4 适用: 大鼠 WB, IHC, ICC, IF, AA 宿主: 小鼠 Monoclonal 7E3 Atto 488
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. In PBS containing 10 % glycerol.
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注意事项
- After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.
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- DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))
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别名
- PSD-95
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背景
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Alternate Names/Synonyms: PSD95, Disks Large Homolog 4, DLG4, Postsynaptic Density Protein 95, Synapse-associated Protein 90, SAP90
Product Description: PSD-95 is a member of proteins located at a specialized postsynaptic membrane region, called the postsynaptic density (PSD). PSD-95 is the most abundant scaffold protein specifically enriched in the PSD. It contains three PDZ domains, an SH3 domain and a guanylate kinase (GuK)-like domain. Through its PDZ domains, PSD-95 assembles various synaptic components at the PSD including intracellular signaling molecules (e.g. SynGAP and kalirin-7), ion channels (e.g. stargazin/AMPA receptors [AMPARs] and NMDA receptors) and cell adhesion molecules (e.g. neuroligin). PSD-95 plays a primary role in synaptic development and maturation and is regulated by palmitoylation at its N-terminal cysteine residues leading to its postsynaptic targeting. Palmitoylation of PSD-95 is triggered by DHHC2, a plasma membrane-inserted palmitoylating enzyme. Palmitoylated PSD-95 is almost exclusively localized at excitatory synapses in neurons.
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途径
- Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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