Asprosin 抗体
Quick Overview for Asprosin 抗体 (ABIN6253475)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-Asprosin (human), mAb (Birdy-2)
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产品特性
- Monoclonal Antibody. Recognizes human asprosin and human fibrillin-1 (by homology). Isotype: Mouse IgG2a. Clone: Birdy-2. Application: ELISA, WB. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. Asprosin is a new fasting-induced protein hormone that targets the liver to increase plasma glucose levels. Asprosin is the C-terminal cleavage product of the protein fibrillin-1. Asprosin is secreted from white adipose tissue and increases hepatic glucose production by using cAMP as a second messenger, leading to activation of protein kinase A in the liver. Reduction of asprosin levels protect against metabolic syndrome-associated hyperinsulinism.
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纯度
- >95 % (SDS-PAGE)
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免疫原
- Recombinant human asprosin.
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亚型
- IgG2a
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anti-Asprosin (AA 2732-2871) antibody
适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.
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- Asprosin
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背景
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Alternate Names/Synonyms: Fibrillin-1 C-terminal Cleavage Product, FBN1 C Terminal Cleavage Product
Product Description: Asprosin is a new fasting-induced protein hormone that targets the liver to increase plasma glucose levels. Asprosin is the C-terminal cleavage product of the protein fibrillin-1. Asprosin is secreted from white adipose tissue and increases hepatic glucose production by using cAMP as a second messenger, leading to activation of protein kinase A in the liver. Reduction of asprosin levels protect against metabolic syndrome-associated hyperinsulinism.
抗原
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