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CD3 抗体 (PE-Cy7)

This PE-Cy7-conjugated 小鼠 单克隆 anti-CD3 antibody (Clone UCHT1) specifically detects CD3 in FACS. The antibody is reactive with 人 samples.
产品编号 ABIN6252999
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD3 抗体 (PE-Cy7) (ABIN6252999)

抗原

See all CD3 抗体
CD3

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD3 antibody is conjugated to PE-Cy7

应用范围

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Flow Cytometry (FACS)

质量等级

GMP Grade

克隆位点

UCHT1
  • 原理

    CD3 PE-Cyanine7 Antibody

    产品特性

    The monoclonal UCHT1 clone recognizes CD3ε antigen, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain (zeta-chain) to generate an activation signal in T lymphocytes. CD3ε is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition. Crosslinking of the TCR via plate bound UCHT1 monoclonal is widely used to study the activation T cell response in vitro.

    纯化方法

    Purified

    纯度

    >95 %

    免疫原

    Human peripheral blood lymphocytes

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    2-8°C, Conjugated antibodies should never be frozen.
  • 抗原

    CD3

    别名

    CD3

    NCBI登录号

    NM_000733

    UniProt

    P07766

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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