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ITGAL 抗体

This anti-ITGAL antibody is a 小鼠 单克隆 antibody detecting ITGAL in FACS. Suitable for 人.
产品编号 ABIN6252976
发货至: 中国

Quick Overview for ITGAL 抗体 (ABIN6252976)

抗原

See all ITGAL 抗体
ITGAL (Integrin alpha-L (ITGAL))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ITGAL antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

质量等级

GMP Grade

克隆位点

TS1-22
  • 原理

    CD11a Unconjugated Antibody

    产品特性

    The clone recognizes a 170-180 kD alpha chain of a type I transmembrane glycoprotein also known as CD11a or LFA-1a. It is also known as LFA-1α. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. CD11a is abundantly expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils but does not express by the non-hematopoietic tissues and platelets. Up-regulation of CD11a on activated lymphocytes is required to induce their immune response. Absence or reduced CD11a expression on tumor cells helps to escape from regular immune surveillance and it may be one of reason of in vivo tumor generation.

    纯化方法

    Purified

    纯度

    >95 %

    免疫原

    Human HLA-DRCTL line cytolytic Tlymphocytes

    亚型

    IgG1, kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    ITGAL (Integrin alpha-L (ITGAL))

    别名

    CD11a

    UniProt

    P20701

    途径

    Activated T Cell Proliferation, Integrin Complex
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