ITGAL 抗体 (FITC)
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Quick Overview for ITGAL 抗体 (FITC) (ABIN6252974)
抗原
See all ITGAL 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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原理
- CD11a FITC Antibody
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产品特性
- The clone recognizes a 170-180 kD alpha chain of a type I transmembrane glycoprotein also known as CD11a or LFA-1a. It is also known as LFA-1a. CD11a non-covalently associates with integrin ß2 (CD18) to form LFA-1. CD11a is abundantly expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils but does not express by the non-hematopoietic tissues and platelets. Up-regulation of CD11a on activated lymphocytes is required to induce their immune response. Absence or reduced CD11a expression on tumor cells helps to escape from regular immune surveillance and it may be one of reason of in vivo tumor generation.
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纯化方法
- Purified
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纯度
- >95 %
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免疫原
- Human HLA-DRCTL line cytolytic Tlymphocytes
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亚型
- IgG1, kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- 2-8°C, Conjugated antibodies should never be frozen.
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- ITGAL (Integrin alpha-L (ITGAL))
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别名
- CD11a
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UniProt
- P20701
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途径
- Activated T Cell Proliferation, Integrin Complex
抗原
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