GP2 抗体 (AA 35-179)
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北京 101111
Quick Overview for GP2 抗体 (AA 35-179) (ABIN6252885)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 35-179
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特异性
- Does not react with Mouse
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纯化方法
- Protein G affinity chromatography
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免疫原
- A partial human recombinant protein corresponding to amino acids 35-179 was used as the immunogen for the GP2 antibody.
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亚型
- IgG2b lambda
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应用备注
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Flow Cytometry: 0.5-1 μg/10e6 cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 min at RT
Optimal dilution of the GP2 antibody should be determined by the researcher. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
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别名
- Glycoprotein 2
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背景
- GP2 (Glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
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基因ID
- 2813
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UniProt
- P55259
抗原
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