RSAD2 抗体 (N-Term)
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Quick Overview for RSAD2 抗体 (N-Term) (ABIN6252810)
抗原
See all RSAD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Protein A affinity chromatography purified antibody
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免疫原
- A recombinant protein fragment from the N-terminal region of human Viperin was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
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Western blot: 3-6 μg/mL
Provided assay concentrations are suggestions only, Viperin antibody titration may be required for optimal results. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- RSAD2 (Radical S-Adenosyl Methionine Domain Containing 2 (RSAD2))
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别名
- Viperin
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背景
- Viral infection induces the interferon (IFN) response which triggers the production of an array of anti-viral proteins. Viperin (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) is expressed in response to IFN-b binding to the IFN receptor, inducing the formation of the IFN-stimulated gene factor 3 complex which then binds to the Viperin promoter. It inhibits many DNA and RNA viruses through a diverse range of mechanisms and is involved in the PRR-mediated innate immune response. Viperin has been shown to be produced in response to TLR3 and TLR4 activation, but not TLR2 and TLR5. It may be involved in the TLR7 and TLR9-induced production of type I IFN by plasmacytoid dendritic cells (pDCs).
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基因ID
- 91543
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UniProt
- Q8WXG1
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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