Villin 1 抗体 (AA 179-311)
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Quick Overview for Villin 1 抗体 (AA 179-311) (ABIN6252737)
抗原
See all Villin 1 (VIL1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 179-311
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纯化方法
- Protein G affinity chromatography
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免疫原
- Amino acids 179-311 from the human protein were used as the immunogen for this Villin antibody.
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亚型
- IgG1 kappa
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应用备注
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Flow Cytometry: 0.5-1 μg/10^6 cells in 0.1ml
IF: 1-2 μg/mL
Western blot: 1-2 μg/mL
IHC (FFPE): 0.25-0.5 μg/mL for 30 min at RT
Titration of the Villin antibody may be required for optimal performance. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Villin 1 (VIL1)
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别名
- Villin
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背景
- Recognizes a protein of ~93 kDa which is identified as Villin (VIL1). It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, Villin is predominantly expressed in tumors of colorectal origin. Antibody to Villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.
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基因ID
- 7429
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UniProt
- P09327
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途径
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization
抗原
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