TXNIP 抗体 (N-Term)
Quick Overview for TXNIP 抗体 (N-Term) (ABIN6252540)
抗原
See all TXNIP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Protein A affinity chromatography
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免疫原
- A recombinant protein fragment from the N-terminal region of human TXNIP was used as the immunogen for this antibody.
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亚型
- IgG
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应用备注
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Western blot: 1-3 μg/mL
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- TXNIP (Thioredoxin Interacting Protein (TXNIP))
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别名
- TXNIP
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背景
- TXNIP (Thioredoxin-interacting protein), also called VDUP1 (Vitamin D3 upregulated protein 1) is a member of the Arrestin family of signal transduction proteins. It is a potent tumor suppressor, blocking tumor growth via blocking cell cycle progression, and reduced expression of TXNIP is found in many tumors. One way TXNIP exerts its tumor suppressive function is by suppressing NF-kB activation, possibly via regulation of the NF-kB subunit p65.
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基因ID
- 10628
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UniProt
- Q9H3M7
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途径
- Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
抗原
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