MAPKAP1 抗体 (C-Term)
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Quick Overview for MAPKAP1 抗体 (C-Term) (ABIN6252515)
抗原
See all MAPKAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Protein A purified antibody
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免疫原
- A recombinant protein fragment from the C-terminal region of human SIN1 was used as the immunogen for this antibody.
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亚型
- IgG
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anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 8-236) antibody
MAPKAP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 370-486) antibodyMAPKAP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 100-150) antibodyMAPKAP1 适用: 人, 小鼠, 大鼠, 犬, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 1-290) antibodyMAPKAP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 85-102) antibodyMAPKAP1 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡, 马, 绵羊, Bat, 猴, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1-3 μg/mL
Provided assay concentrations are suggestions only, SIN1 antibody titration may be required for optimal results. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
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别名
- SIN1
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背景
- MTOR, or Mammalian target of rapamycin, a large protein kinase, is a regulator of cell growth and survival via its mTORC1 (mTOR + GBL + Raptor) and mTORC2 (mTOR + GBL + SIN1 + Rictor) complexes. SIN1 is an essential component of mTORC2, which activates Akt by phosphorylating Ser473. Phosphorylation of SIN1 at Thr86/398 causes its dissociation from the mTORC2 complex, inhibiting mTORC2s kinase activity.
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基因ID
- 79109
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UniProt
- Q9BPZ7
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途径
- PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events
抗原
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