NKIRAS1 抗体
Quick Overview for NKIRAS1 抗体 (ABIN6252507)
抗原
See all NKIRAS1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G purified antibody
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免疫原
- A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody.
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亚型
- IgG1 kappa
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应用备注
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Western blot: 5-10 μg/mL
Provided assay concentrations are suggestions only, NKIRAS1 antibody titration may be required for optimal results. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))
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别名
- NKIRAS1
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背景
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NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.
NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity.
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基因ID
- 28512
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UniProt
- Q9NYS0
抗原
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