Filaggrin 抗体 (AA 998-1104)
Quick Overview for Filaggrin 抗体 (AA 998-1104) (ABIN6252503)
抗原
See all Filaggrin (FLG) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 998-1104
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纯化方法
- Protein G affinity chromatography
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免疫原
- Amino acids 998-1104 of human FLG were used as the immunogen for this Filaggrin antibody.
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亚型
- IgG1 kappa
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anti-Filaggrin (FLG) (AA 119-336) antibody
FLG 适用: 小鼠 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (AA 998-1104) antibodyFLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FLG-1563 unconjugated
anti-Filaggrin (FLG) (AA 198-288) antibodyFLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FLG-1561 unconjugated
anti-Filaggrin (FLG) (AA 3838-4061) antibodyFLG 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (AA 198-288) antibodyFLG 适用: 人 IHC, ISt, StM 宿主: 兔 Monoclonal FLG-1957R unconjugated Recombinant Antibody
anti-Filaggrin (FLG) (AA 198-288) antibodyFLG 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal rFLG-1561 unconjugated Recombinant Antibody
anti-Filaggrin (FLG) antibodyFLG 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (AA 3905-4031) antibodyFLG 适用: 人 IHC, WB, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (pTyr654) antibodyFLG 适用: 人, 小鼠, 大鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Filaggrin (FLG) (pTyr154) antibodyFLG 适用: 人, 小鼠, 大鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow Cytometry: 0.5-1 μg/10^6 cells in 0.1ml
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
Optimal dilution of the Filaggrin antibody should be determined by the researcher. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Filaggrin (FLG)
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别名
- Filaggrin
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背景
- Filaggrin (FLG) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple Filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional Filaggrin molecules. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
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基因ID
- 2312
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UniProt
- P20930
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途径
- Sensory Perception of Sound, Stem Cell Maintenance
抗原
-
