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FSHR 抗体

FSHR 适用: 人 IHC, IF, FACS 宿主: 小鼠 Monoclonal FSHR-1400 unconjugated
产品编号 ABIN6252490
发货至: 中国
  • 抗原 See all FSHR 抗体
    FSHR (Follicle Stimulating Hormone Receptor (FSHR))
    适用
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    宿主
    • 63
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    小鼠
    克隆类型
    • 64
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    单克隆
    标记
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    This FSHR antibody is un-conjugated
    应用范围
    • 58
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    Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    Protein G affinity chromatography
    免疫原
    A human recombinant protein was used as the immunogen for this FSHR antibody.
    克隆位点
    FSHR-1400
    亚型
    IgG1 kappa
    Top Product
    Discover our top product FSHR Primary Antibody
  • 应用备注
    Flow Cytometry: 0.5-1 μg/10^6 cells

    IF: 1-2 μg/mL

    IHC (FFPE): 1-2 μg/mL for 30 min at RT

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FSHR antibody to be titered up or down for optimal performance.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原
    FSHR (Follicle Stimulating Hormone Receptor (FSHR))
    别名
    FSH Receptor (FSHR 产品)
    别名
    FSHRO antibody, LGR1 antibody, ODG1 antibody, FSH-R antibody, eFSHR antibody, FSHRE antibody, fshr antibody, FSHR antibody, fshr-A antibody, GTHR-I antibody, zfGTHR-I antibody, LOC100304505 antibody, follicle stimulating hormone receptor antibody, follicle stimulating hormone receptor L homeolog antibody, follicle-stimulating hormone receptor antibody, FSHR antibody, fshr antibody, Fshr antibody, fshr.L antibody, Bm1_17785 antibody, LOC100304505 antibody
    背景
    Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its alpha and beta subunits. While the alpha subunit of FSH is involved in the binding of FSH to the receptor, the beta subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome, a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells.
    基因ID
    2492
    UniProt
    P23945
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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