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CD16 抗体

CD16 适用: 人 FACS, IF, WB, Func 宿主: 小鼠 Monoclonal HuNK2 unconjugated
产品编号 ABIN6252333
发货至: 中国
  • 抗原 See all CD16 抗体
    CD16
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD16 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Functional Studies (Func)
    纯化方法
    Protein G affinity chromatography
    免疫原
    Human peripheral blood lymphocytes from a NK-leukemia patient were used as the immunogen for the CD16 antibody.
    克隆位点
    HuNK2
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD16 Primary Antibody
  • 应用备注
    Functional Activity (Order SAF formulation)

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

    Immunofluorescence: 0.5-1 μg/mL

    Optimal dilution of the CD16 antibody should be determined by the researcher.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.2 mg/mL
    缓冲液
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原
    CD16
    别名
    CD16 (CD16 产品)
    别名
    Fcgr3 antibody, Fcgr3a antibody, CD16 antibody, FCGR3 antibody, FCGR3@ antibody, CD16b antibody, FCG3 antibody, FCR-10 antibody, FCRIII antibody, FCRIIIb antibody, FcRIII antibody, Fc fragment of IgG, low affinity IIa, receptor antibody, Fc fragment of IgG, low affinity IIIa, receptor (CD16a) antibody, Fc fragment of IgG receptor IIIb antibody, Fc fragment of IgG receptor IIIa antibody, Fc receptor, IgG, low affinity III antibody, Fc-gamma RIII antibody, Fcgr2a antibody, FCGR3A antibody, FCGR3B antibody, Fcgr3 antibody, FCGR3 antibody
    背景
    Recognizes a protein of 50-65  kDa, identified as CD16 (Workshop IV, Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This mAb has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.
    基因ID
    2214
    UniProt
    P08637
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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