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FLI1 抗体 (AA 107-216)

This 小鼠 单克隆 anti-FLI1 antibody (Clone FLVI1-1) specifically detects FLI1 in WB, IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN6252309
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for FLI1 抗体 (AA 107-216) (ABIN6252309)

抗原

See all FLI1 抗体
FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

适用

  • 91
  • 46
  • 21
  • 9
  • 6
  • 6
  • 6
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4

宿主

  • 71
  • 20
  • 1
小鼠

克隆类型

  • 50
  • 42
单克隆

标记

  • 52
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FLI1 antibody is un-conjugated

应用范围

  • 79
  • 38
  • 30
  • 25
  • 16
  • 10
  • 8
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

FLVI1-1
  • 抗原表位

    • 12
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-216

    纯化方法

    Protein G affinity chromatography

    免疫原

    Human partial recombinant protein (amino acids 107-216) was used as the immunogen for this FLI1 antibody.

    亚型

    IgG
  • 应用备注

    Western blot: 1-2 μg/m,l

    Flow Cytometry: 0.5-1 μg/10^6 cells

    IF: 1-2 μg/mL

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FLI1 antibody to be titered up or down for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原

    FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

    别名

    FLI1

    背景

    Friend leukemia integration 1 is a member of the ETS family of DNA binding transcription factors that is involved in cellular proliferation and tumorigenesis. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90 % of Ewing's Sarcoma (EWS) / Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11,22)(q24,q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi's Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.

    基因ID

    2313

    UniProt

    Q01543
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