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PTH 抗体 (N-Term)

The 兔 多克隆 anti-PTH antibody is suitable to detect PTH in samples from 人. It has been validated for IF, FACS 和 IHC (p).
产品编号 ABIN6252109
发货至: 中国
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Quick Overview for PTH 抗体 (N-Term) (ABIN6252109)

抗原

See all PTH 抗体
PTH (Parathyroid Hormone (PTH))

适用

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宿主

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克隆类型

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多克隆

标记

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This PTH antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    N-Term

    纯化方法

    Protein A affinity chromatography

    免疫原

    A synthetic peptide from the N-terminal region of human Parathyroid hormone was used as the immunogen for the PTH antibody.

    亚型

    IgG
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

    Immunofluorescence: 0.5-1 μg/mL

    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT

    Optimal dilution of the PTH antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原

    PTH (Parathyroid Hormone (PTH))

    别名

    Parathyroid Hormone

    物质类

    Hormone

    背景

    PTH/Parathyroid hormone is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.

    基因ID

    5741

    UniProt

    P01270

    途径

    cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
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