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S100A9 抗体

This anti-S100A9 antibody is a 小鼠 单克隆 antibody detecting S100A9 in IF 和 IHC (p). Suitable for 人.
产品编号 ABIN6251943
发货至: 中国

Quick Overview for S100A9 抗体 (ABIN6251943)

抗原

See all S100A9 抗体
S100A9 (S100 Calcium Binding Protein A9 (S100A9))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This S100A9 antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

PS1A9-1
  • 纯化方法

    PEG precipitation

    免疫原

    Recombinant human protein was used as the immunogen for the S100A9 antibody.

    亚型

    IgM kappa
  • 应用备注

    Immunofluorescence: 1-2 μg/mL

    Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT (1)

    Titering of the S100A9 antibody may be required for optimal performance.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Not suitable for frozen tissue testing.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原

    S100A9 (S100 Calcium Binding Protein A9 (S100A9))

    别名

    S100A9

    背景

    S100A9, also known as Calgranulin B or MRP14, is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. [UniProt]

    基因ID

    6280

    UniProt

    P06702

    途径

    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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