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Thrombomodulin 抗体 (AA 69-194)

This anti-Thrombomodulin antibody is a 小鼠 单克隆 antibody detecting Thrombomodulin in WB, ELISA, FACS, IF 和 IHC (p). Suitable for 人.
产品编号 ABIN6251861
发货至: 中国
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Quick Overview for Thrombomodulin 抗体 (AA 69-194) (ABIN6251861)

抗原

See all Thrombomodulin (THBD) 抗体
Thrombomodulin (THBD)

适用

  • 136
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宿主

  • 98
  • 62
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小鼠

克隆类型

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  • 1
单克隆

标记

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This Thrombomodulin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

THBD-1782
  • 抗原表位

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    • 3
    • 3
    • 3
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    AA 69-194

    纯化方法

    Protein G affinity chromatography

    免疫原

    Human recombinant partial protein corresponding to amino acids 69-194 was used as the immunogen for this Thrombomodulin antibody.

    亚型

    IgG2a kappa
  • 应用备注

    Flow Cytometry: 0.5-1 μg/10^6 cells in 0.1ml

    IF: 0.5-1 μg/mL

    IHC (FFPE): 1-2 μg/mL for 30 min at RT

    ELISA: 2-4 μg/mL, order the BSA-free formulation for coating

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Thrombomodulin antibody to be titered up or down for optimal performance.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • 抗原

    Thrombomodulin (THBD)

    别名

    Thrombomodulin

    背景

    It recognizes a protein of 75  kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.

    基因ID

    7056

    UniProt

    P07204
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