Thrombomodulin 抗体 (AA 69-194)
Quick Overview for Thrombomodulin 抗体 (AA 69-194) (ABIN6251860)
抗原
See all Thrombomodulin (THBD) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 69-194
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纯化方法
- Protein G affinity chromatography
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免疫原
- Human recombinant partial protein corresponding to amino acids 69-194 was used as the immunogen for this Thrombomodulin antibody.
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亚型
- IgG2b kappa
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应用备注
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Flow Cytometry: 0.5-1 μg/10^6 cells in 0.1ml
IF: 0.5-1 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 min at RT
ELISA: 2-4 μg/mL, order the BSA-free formulation for coating
WB: 0.5-1 μg/mL
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Thrombomodulin antibody to be titered up or down for optimal performance. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Thrombomodulin (THBD)
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别名
- Thrombomodulin
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背景
- It recognizes a protein of 75 kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
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基因ID
- 7056
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UniProt
- P07204
抗原
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