Integrin beta 4 抗体
Quick Overview for Integrin beta 4 抗体 (ABIN6251855)
抗原
See all Integrin beta 4 (ITGB4) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein G affinity chromatography
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免疫原
- The human squamous cell carcinoma line (UM-SCC1) was used as the immunogen for this Integrin beta-4 / CD104 antibody.
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亚型
- IgG2a kappa
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anti-Integrin beta 4 (ITGB4) (AA 29-206) antibody
ITGB4 适用: 人 IHC, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 1D6B4 unconjugated
anti-Integrin beta 4 (ITGB4) (AA 29-206) antibodyITGB4 适用: 人 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 5G3G5 unconjugated
anti-Integrin beta 4 (ITGB4) (AA 1401-1533) antibodyITGB4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (C-Term) antibodyITGB4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 28-310) antibodyITGB4 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (Tyr1510) antibodyITGB4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 28-137) antibodyITGB4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) antibodyITGB4 适用: 人, 雪貂, Mustelid WB, FACS, IP, IF, IHC (fro) 宿主: 小鼠 Monoclonal 450-9D unconjugated
anti-Integrin beta 4 (ITGB4) (AA 28-266) antibodyITGB4 适用: 人 WB, IHC, FACS, IF, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 4 (ITGB4) (AA 1098-1356) antibodyITGB4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Functional Blocking: partially blocks laminin binding, order the BSA/azide free format
Flow Cytometry: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Integrin beta 4 (ITGB4)
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别名
- Integrin Beta-4
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背景
- This antibody recognizes a protein of 205 kDa, which is identified as integrin beta 4 (ITGB4) and CD104. Its epitope is localized in the extracellular domain of integrin beta 4 protein. Integrins are heterodimers comprised of < font face=symbol>a and < font face=symbol>b subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of < font face=symbol>a and < font face=symbol>b polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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基因ID
- 3691
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UniProt
- P16144
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途径
- Integrin Complex
抗原
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