Mare/Nprl3/C16orf35 抗体 (AA 86-117)
Quick Overview for Mare/Nprl3/C16orf35 抗体 (AA 86-117) (ABIN6244303)
抗原
See all Mare/Nprl3/C16orf35 (C16orf35) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 86-117
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This NPRL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 86-117 amino acids from human NPRL3.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))
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别名
- NPRL3
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背景
- As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC- containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.
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分子量
- 63605
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UniProt
- Q12980
抗原
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