H3F3B 抗体 (AA 31-65)
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北京 101111
Quick Overview for H3F3B 抗体 (AA 31-65) (ABIN6244250)
抗原
See all H3F3B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 31-65
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This H3f3b antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 31-65 amino acids from human H3f3b.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- H3F3B (H3 Histone, Family 3B (H3.3B) (H3F3B))
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别名
- H3f3b
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背景
- Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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分子量
- 15328
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UniProt
- P84244
抗原
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