电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

NDEL1 抗体 (AA 178-213)

This anti-NDEL1 antibody (ABIN6244172) is a Rabbit Polyclonal antibody detecting NDEL1 in WB. Suitable for Human, Mouse.
产品编号 ABIN6244172
发货至: 中国

Quick Overview for NDEL1 抗体 (AA 178-213) (ABIN6244172)

抗原

See all NDEL1 抗体
NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))

适用

  • 66
  • 54
  • 49
  • 2
  • 1
人, 小鼠

宿主

  • 88
  • 5
  • 1

克隆类型

  • 79
  • 15
多克隆

标记

  • 24
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This NDEL1 antibody is un-conjugated

应用范围

  • 52
  • 52
  • 49
  • 21
  • 14
  • 12
  • 7
  • 5
  • 5
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB50842
  • 抗原表位

    • 22
    • 15
    • 15
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 178-213

    预测反应

    C, Pr, Rb, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This NDEL1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 178-213 amino acids from the Central region of human NDEL1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    NDEL1 (NudE Nuclear Distribution E Homolog (A. Nidulans)-Like 1 (NDEL1))

    别名

    NDEL1

    背景

    Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL.

    分子量

    38375

    UniProt

    Q9GZM8

    途径

    Regulation of Cell Size
You are here:
Chat with us!