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- 抗原 See all FHIT 抗体
- FHIT (Fragile Histidine Triad (FHIT))
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抗原表位
- AA 19-54
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FHIT antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This FHIT antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between19-54 amino acids from human FHIT.
- 克隆位点
- RB53956
- 亚型
- Ig Fraction
- Top Product
- Discover our top product FHIT Primary Antibody
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anti-Fragile Histidine Triad (FHIT) (AA 25-147) antibody
FHIT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fragile Histidine Triad (FHIT) (AA 1-147) antibodyFHIT 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fragile Histidine Triad (FHIT) (Internal Region) antibodyFHIT 适用: 人, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fragile Histidine Triad (FHIT) antibodyFHIT 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fragile Histidine Triad (FHIT) (AA 31-130) antibodyFHIT 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1H2 unconjugated
anti-Fragile Histidine Triad (FHIT) (AA 31-147) antibodyFHIT 适用: 人 ELISA, WB, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fragile Histidine Triad (FHIT) (AA 2-147) antibodyFHIT 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fragile Histidine Triad (FHIT) antibodyFHIT 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Fragile Histidine Triad (FHIT) (AA 31-130) antibodyFHIT 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Fragile Histidine Triad (FHIT) (AA 31-130) antibodyFHIT 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1C3 unconjugated
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- 应用备注
- WB: 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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- 抗原
- FHIT (Fragile Histidine Triad (FHIT))
- 别名
- FHIT (FHIT 产品)
- 别名
- AP3Aase antibody, FRA3B antibody, FHIT antibody, zgc:73176 antibody, AW045638 antibody, Fra14A2 antibody, LOC100223655 antibody, fragile histidine triad antibody, fragile histidine triad gene antibody, fragile histidine triad protein antibody, fragile histidine triad L homeolog antibody, FHIT antibody, Fhit antibody, fhit antibody, PY07476 antibody, fhit.L antibody
- 背景
- Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'- adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 signaling pathways. Inhibits MDM2-mediated proteasomal degradation of p53/TP53 and thereby plays a role in p53/TP53-mediated apoptosis. Induction of apoptosis depends on the ability of FHIT to bind P(1)-P(3)-bis(5'-adenosyl) triphosphate or related compounds, but does not require its catalytic activity, it may in part come from the mitochondrial form, which sensitizes the low- affinity Ca(2+) transporters, enhancing mitochondrial calcium uptake. Functions as tumor suppressor.
- 分子量
- 16858
- UniProt
- P49789
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