SOX7 抗体 (AA 224-258)
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Quick Overview for SOX7 抗体 (AA 224-258) (ABIN6244006)
抗原
See all SOX7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 224-258
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SOX7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 224-258 amino acids from the Central region of human SOX7.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))
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别名
- SOX7
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背景
- Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'.
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分子量
- 42197
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UniProt
- Q9BT81
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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