RBX1 抗体 (AA 1-108)
Quick Overview for RBX1 抗体 (AA 1-108) (ABIN6243992)
抗原
See all RBX1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-108
-
预测反应
- M
-
纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
-
免疫原
- This antibody is generated from a mouse immunized with a recombinant protein between 1-108 amino acids from human.
-
亚型
- IgG1 kappa
-
-
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 74-108), (C-Term) antibody
RBX1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB48352 unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 1-108) antibodyRBX1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 1-108) antibodyRBX1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (C-Term) antibodyRBX1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 1-50) antibodyRBX1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 小鸡, 马 WB, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (AA 1-100) antibodyRBX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1) (Middle Region) antibodyRBX1 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:4000. WB: 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
有效期
- 6 months
-
-
- RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))
-
别名
- RBX1
-
背景
- E3 ubiquitin ligase component of multiple cullin-RING- based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair. The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components. As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, like CDC34, to the complex and brings it into close proximity to the substrate. Probably also stimulates CDC34 autoubiquitination. May be required for histone H3 and histone H4 ubiquitination in response to ultraviolet and for subsequent DNA repair. Promotes the neddylation of CUL1, CUL2, CUL4 and CUL4 via its interaction with UBE2M. Involved in the ubiquitination of KEAP1, ENC1 and KLHL41. In concert with ATF2 and CUL3, promotes degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM.
-
分子量
- 12274
-
UniProt
- P62877
-
途径
- Cell Division Cycle, M Phase, SARS-CoV-2 Protein Interactome
抗原
-
