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ZAP70 抗体 (AA 252-282)

This 兔 多克隆 anti-ZAP70 antibody (Clone RB3100) specifically detects ZAP70 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN6243970
发货至: 中国
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Room 801-803
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Quick Overview for ZAP70 抗体 (AA 252-282) (ABIN6243970)

抗原

See all ZAP70 抗体
ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

适用

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宿主

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克隆类型

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多克隆

标记

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This ZAP70 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB3100
  • 抗原表位

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    AA 252-282

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ZAP70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-282 amino acids from the Central region of human ZAP70.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

    别名

    ZAP70

    背景

    This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.

    分子量

    69872

    NCBI登录号

    NP_001070, NP_997402

    UniProt

    P43403

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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