PAFAH1B1 抗体 (N-Term)
Quick Overview for PAFAH1B1 抗体 (N-Term) (ABIN6243934)
抗原
See all PAFAH1B1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 76-110, N-Term
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预测反应
- B, C, Pr, Pig
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PAFAH1B1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 76-110 amino acids from the N-terminal region of human PAFAH1B1.
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亚型
- Ig Fraction
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anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (C-Term) antibody
Verified PAFAH1B1 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (AA 1-110) antibodyPAFAH1B1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5A5 unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) antibodyPAFAH1B1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (N-Term) antibodyPAFAH1B1 适用: 人, 大鼠, 小鼠, Cow, 犬, 斑马鱼, 马, 兔, Pig, 豚鼠, 小鸡, 非洲爪蟾, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (AA 311-410) antibodyPAFAH1B1 适用: 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) antibodyPAFAH1B1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (AA 40-155) antibodyPAFAH1B1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (AA 1-110) antibodyPAFAH1B1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (C-Term) antibodyPAFAH1B1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1) (AA 71-120) antibodyPAFAH1B1 适用: 人, 大鼠, 小鼠, Cow, 犬, 马, 兔, Pig, 豚鼠, 小鸡, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- PAFAH1B1 (Platelet-Activating Factor Acetylhydrolase 1b, Regulatory Subunit 1 (45kDa) (PAFAH1B1))
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别名
- PAFAH1B1
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背景
- Required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet- activating factor (PAF) by removing the acetyl group at the SN-2 position (By similarity). Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing.
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分子量
- 46638
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UniProt
- P43034
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途径
- M Phase, Regulation of Cell Size
抗原
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